The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab68482 is purified by proprietary chromatographic techniques.
Purity is greater than 95.0% as determined by analysis by RP-HPLC and SDS-PAGE.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.0045 mM Sodium bicarbonate.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitute in sterile 18MOhms/cm water to not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Leptin (murine obesity homolog)
Leptin (obesity homolog, mouse)
Leptin Murine Obesity Homolog
Leptin Precursor Obesity Factor
Obese, mouse, homolog of
Obesity homolog mouse
Obesity Murine Homolog Leptin
May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
Involvement in disease
Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.