For the best experience on the Abcam website please upgrade to a modern browser such as
Source Escherichia coli
Amino Acid Sequence
Sequence MQRKRRNTIH EFKKSAKTTL IKIDPALKIK TKKVNTADQC ANRCTRNKGL PFTCKAFVFD KARKQCLWFP FNSMSSGVKK EFGHEFDLYE NKDYIRNCII GKGRSYKGTV SITKSGIKCQ PWSSMIPHEH SYRGKDLQEN YCRNPRGEEG GPWCFTSNPE VRYEVCDIPQ CSEVECMTCN GESYRGLMDH TESGKICQRW DHQTPHRHKF LPERYPDKGF DDNYCRNPDG QPRPWCYTLD PHTRWEYCAI KTCET.
Molecular weight 30 kDa
Amino acids 32 to 285
Additional sequence information HGF Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 255 amino acids (32-285 a.a.) and having a molecular mass of 29.8kDa. Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 95
% SDS-PAGE. This product is purified by proprietary chromatographic techniques.
Purity: Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Additional notes For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.0045mM Sodium Bicarbonate.
Reconstitution Reconstitute in sterile 18MOhm/cm H 2O to not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Function This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
Tissue specificity Expressed in breast, placenta, kidney, liver and pancreas.
Sequence similarities Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains.
Domain The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.
Cellular localization Secreted and Membrane.
Information by UniProt
References for Recombinant Cow Prolactin Receptor protein (ab73249)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"