The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Endotoxin level< 0.100 Eu/µg
Additional notesThe biological activity of this product is determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
C-X-C motif chemokine 2
Chemokine (C X C motif) ligand 2
Chemokine, CXC motif, ligand 2
Cytokine-induced neutrophil chemoattractant 3
GRO protein, beta
Growth regulated protein beta
Growth-regulated protein beta
Hematopoietic synergistic factor
Macrophage inflammatory protein 2
Macrophage inflammatory protein 2 alpha
Macrophage inflammatory protein 2-alpha
Melanoma growth stimulatory activity beta
Small inducible cytokine subfamily B, member 2
FunctionProduced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
Post-translational modificationsThe N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.