Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Immunohistochemistry (Frozen sections)

    Functional Studies

    SDS-PAGE

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Additional notesThe biological activity of this product was determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • C-X-C motif chemokine 2
    • Chemokine (C X C motif) ligand 2
    • Chemokine, CXC motif, ligand 2
    • CINC 2a
    • CINC2a
    • CINC3
    • CXC chemokine
    • CXCL 2
    • Cxcl2
    • CXCL2_HUMAN
    • Cytokine-induced neutrophil chemoattractant 3
    • GRO 2
    • GRO b
    • GRO protein, beta
    • Gro-beta
    • GRO-beta(5-73)
    • GRO-beta-T
    • GRO2
    • GRO2 oncogene
    • GROb
    • GRObeta
    • Growth regulated protein beta
    • Growth-regulated protein beta
    • GROX
    • Hematopoietic synergistic factor
    • HSF
    • Macrophage inflammatory protein 2
    • Macrophage inflammatory protein 2 alpha
    • Macrophage inflammatory protein 2-alpha
    • Melanoma growth stimulatory activity beta
    • MGSA b
    • MGSA beta
    • MIP 2
    • MIP 2a
    • MIP2
    • MIP2 alpha
    • MIP2-alpha
    • MIP2A
    • MIP2alpha
    • SB-251353
    • Scyb
    • SCYB 2
    • SCYB2
    • Small inducible cytokine subfamily B, member 2
    see all
  • FunctionProduced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
  • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant CXCL2 protein (ab9952)

This product has been referenced in:
  • Xu J  et al. Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury. Am J Physiol Gastrointest Liver Physiol 287:G734-41 (2004). Read more (PubMed: 15130876) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"