Recombinant Cytomegalovirus pp65 protein (ab43041)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Cytomegalovirus
    • Molecular weight
      63 kDa
    • Additional sequence information
      The protein contains the Full Length of CMV Pp65 (UL83). Contains a 6x His Tag.

Specifications

Our Abpromise guarantee covers the use of ab43041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Immunoreactive with sera of CMV infected individuals.
  • Applications

    ELISA

    Western blot

  • Purity
    > 95 % SDS-PAGE.
    Sepharose derived purification.
  • Form
    Liquid
  • Additional notes

    Specificity: Immunoreactive with sera of CMV-infected individuals.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 25mM Tris HCl, 1mM EDTA, pH 7.2

General Info

  • Alternative names
    • 65 kDa matrix phosphoprotein
    • 65 kDa phosphoprotein
    • Tegument protein pp65
    • Tegument protein UL83
  • Relevance
    Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period. CMV viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. pp65 is a 65kD phosphorylated glycoprotein and is the most abundant of the late antigens.

References

ab43041 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Gracias por contactarnos.
Lamentablemente ni ésta ni ninguna de las otras proteínas Cytomegalovirus pp65 disponibles en el catálogo se han usado en ensayos ELISPOT. Sin embargo, al ser una técnica muy similar al ELISA es muy posible que funcione. ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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