Recombinant E. coli PANK1 protein (ab123146)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Escherichia coli
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMGSHMSIKEQTLMTPYLQFDRNQWAALRDS VPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVL EQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITT DGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYS HLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFS IYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT LWKEINWLNLKQNILPTRERASLI LTKSANHAVEEVRLRK
    • Molecular weight
      39 kDa including tags
    • Amino acids
      1 to 316
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab123146 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab123146 was purified using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 10% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names
    • coaA
    • hPanK
    • hPanK1
    • PANK
    • PANK1
    • PANK1_HUMAN
    • PANK1a
    • PANK1b
    • PanK1beta
    • Pantothenate kinase
    • Pantothenate kinase 1
    • Pantothenic acid kinase 1
    see all
  • Function
    Plays a role in the physiological regulation of the intracellular CoA concentration.
  • Tissue specificity
    Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.
  • Pathway
    Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
  • Sequence similarities
    Belongs to the type II pantothenate kinase family.
  • Domain
    The N-terminal extension, present in isoform 1 may be the regulatory domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS PAGE, 3 µg of ab123146 loaded.

References

ab123146 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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