Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Escherichia coli
    • Molecular weight
      19 kDa
    • Amino acids
      2 to 178

Specifications

Our Abpromise guarantee covers the use of ab123224 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

    pH: 7.60
    Constituents: 0.02% DTT, 0.32% Tris HCl, 0.03% EDTA, 50% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names
    • Autoantigen La
    • La
    • La autoantigen
    • La autoantigen homolog
    • La protein
    • La ribonucleoprotein
    • La ribonucleoprotein domain family member 3
    • LA_HUMAN
    • LARP3
    • Lupus La antigen
    • Lupus La protein
    • Lupus La protein homolog
    • MGC118101
    • MGC93380
    • mRNA for autoantigen
    • OTTMUSP00000014043
    • RP23 273G23.1
    • Sjoegren syndrome type B antigen
    • Sjogren syndrome antigen B
    • Sjogren syndrome antigen B (autoantigen La)
    • SS B
    • SS-B
    • SS-B/La protein
    • SSB
    see all
  • Function
    Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
  • Sequence similarities
    Contains 1 HTH La-type RNA-binding domain.
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    modifications
    Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.
    The N-terminus is blocked.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE of ab123224

References

This product has been referenced in:
  • Krauss G  et al. Escherichia coli single-strand deoxyribonucleic acid binding protein: stability, specificity, and kinetics of complexes with oligonucleotides and deoxyribonucleic acid. Biochemistry 20:5346-52 (1981). Read more (PubMed: 7028102) »
  • Weiner JH  et al. The deoxyribonucleic acid unwinding protein of Escherichia coli. Properties and functions in replication. J Biol Chem 250:1972-80 (1975). Read more (PubMed: 1090613) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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