Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Amino acids
      1 to 162
    • Tags
      proprietary tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab68365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    This protein is immunoreactive with sera of EBV-infected individuals.
  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    This protein was purified by proprietary chromatographic techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 25mM Glycine, pH 9.6

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • EBV
    • Epstein Barr virus p23 protein
    • HHV4 p23
    • Human Herpesvirus 4
    • Probable capsid protein VP23
    • Protein BDLF1
    • VP23
    see all
  • Relevance
    The Epstein Barr virus (EBV) is a human herpes virus 4 (HHV4) that infects and establishes latency in B-lymphocytes. Primary infection leads to a life-long past infection which is normally asymptomatic. EBV expresses a number of genes, however, Epstein Barr nuclear antigen 1 (EBNA1) p72 is the only viral protein which characterizes EBV past-infection. p23 is one of the two small viral capsid antigens (VCA). EBV p23 is a viral late complex associated with virion particles and consists of two gene products, BFRF3 and BLRF2. EBV has a worldwide distribution, with over 90% of the adult population showing evidence of past infection. The virus, acquired during childhood, usually causes no symptoms. However, in Western societies, 10 to 20% of adolescents and young adults develop acute infectious mononucleosis (IM). In humans, EBV is also associated with cancer, in particular Burkitt's lymphoma, nasopharyngeal carcinoma, Hodgkin's disease, and immunoblastic lymphoma.
  • Cellular localization
    virion

References

ab68365 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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