This product is an active protein and may elicit a biological response in vivo, handle with caution.
Epstein Barr virus p23 protein
Human Herpesvirus 4
Probable capsid protein VP23
RelevanceThe Epstein Barr virus (EBV) is a human herpes virus 4 (HHV4) that infects and establishes latency in B-lymphocytes. Primary infection leads to a life-long past infection which is normally asymptomatic. EBV expresses a number of genes, however, Epstein Barr nuclear antigen 1 (EBNA1) p72 is the only viral protein which characterizes EBV past-infection.
p23 is one of the two small viral capsid antigens (VCA). EBV p23 is a viral late complex associated with virion particles and consists of two gene products, BFRF3 and BLRF2.
EBV has a worldwide distribution, with over 90% of the adult population showing evidence of past infection. The virus, acquired during childhood, usually causes no symptoms. However, in Western societies, 10 to 20% of adolescents and young adults develop acute infectious mononucleosis (IM). In humans, EBV is also associated with cancer, in particular Burkitt's lymphoma, nasopharyngeal carcinoma, Hodgkin's disease, and immunoblastic lymphoma.
References for Recombinant EBV p23 protein (ab68365)
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