Recombinant Growth Hormone protein (ab68393)



  • Nature
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Gilthead seabream
    • Sequence
      The sequence of the first five N-terminal amino acids was determined and was found to be Thr-Asp-Gly-Gln-Arg-Leu.


Our Abpromise guarantee covers the use of ab68393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies


  • Purity
    > 95 % SDS-PAGE.
    ab68393 was purified by proprietary chromatographic techniques. Purity is greater than 98.0% as determined by analysis by RP-HPLC and SDS-PAGE.
  • Form
  • Additional notes
    For long term storage and more diluted solutions it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservatives: None.
    Constituents: 0.02% Sodium bicarbonate.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute in 0.4% NaHCO3 or water adjusted to pH 8-9, to not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in a presence of a carrier protein such as BSA or similar.

General Info

  • Alternative names
    • gH
    • GH-N
    • GH1
    • GHB5
    • GHN
    • Growth hormone
    • Growth hormone 1
    • Growth hormone B5
    • Growth hormone, normal
    • Growth hormone, pituitary
    • HG1
    • hGH-N
    • IGHD1B
    • Pituitary growth hormone
    • RNGHGP
    • Somatotropin
    see all
  • Function
    Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
  • Involvement in disease
    Defects in GH1 are a cause of growth hormone deficiency isolated type 1A (IGHD1A) [MIM:262400]; also known as pituitary dwarfism I. IGHD1A is an autosomal recessive deficiency of GH which causes short stature. IGHD1A patients have an absence of GH with severe dwarfism and often develop anti-GH antibodies when given exogenous GH.
    Defects in GH1 are a cause of growth hormone deficiency isolated type 1B (IGHD1B) [MIM:612781]; also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH. Dwarfism is less severe than in IGHD1A and patients usually respond well to exogenous GH.
    Defects in GH1 are the cause of Kowarski syndrome (KWKS) [MIM:262650]; also known as pituitary dwarfism VI.
    Defects in GH1 are a cause of growth hormone deficiency isolated type 2 (IGHD2) [MIM:173100]. IGHD2 is an autosomal dominant deficiency of GH which causes short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy.
  • Sequence similarities
    Belongs to the somatotropin/prolactin family.
  • Cellular localization
  • Information by UniProt

References for Recombinant Growth Hormone protein (ab68393)

ab68393 has not yet been referenced specifically in any publications.

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