Recombinant HCC1 protein (ab9846)

Overview

  • Product nameRecombinant HCC1 protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Additional notesThe biological activity of this product is determined by its ability to chemoattract human monocytes using a concentration range of 5.0-20.0 ng/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • CAPER
    • CAPER alpha
    • CAPERalpha
    • CC1.3
    • Coactivator of activating protein 1 and estrogen receptors
    • Coactivator of AP1 and ERs
    • DKFZp781C0423
    • FLJ44170
    • HCC 1
    • Hepatocellular carcinoma protein 1
    • RBM 39
    • RBM39
    • RBM39_HUMAN
    • RNA binding motif protein 39
    • RNA binding region (RNP1 RRM) containing 2
    • RNA binding region containing 2
    • RNA binding region containing protein 2
    • RNA-binding motif protein 39
    • RNA-binding protein 39
    • RNA-binding region-containing protein 2
    • RNPC 2
    • RNPC2
    • Splicing factor CC1.3
    • Splicing factor CC1.4
    • Splicing factor HCC 1
    • Splicing factor HCC1
    • Transcription coactivator CAPER
    see all
  • FunctionTranscriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.
  • Tissue specificityWidely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain. Expressed at intermediate level in kidney, liver and heart.
  • Sequence similaritiesBelongs to the splicing factor SR family.
    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localizationNucleus speckle. Concentrated in nuclear speckles. Colocalizes with the core spliceosomal snRNP proteins.
  • Information by UniProt

References for Recombinant HCC1 protein (ab9846)

ab9846 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Yes, you are correct this recombinant protein has been incorrectly listed in the relevance section, the swissprot links and the research area on the datasheet of ab9846. Please accept my apolagies. The recombinant protein...

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I have checked the datasheet for ab9845 -- Rabbit polyclonal to human HCC 1 and note the antibody can be used at a concentration of 0.1 - 0.2 µg/ml and that the detection limit for hHCC-1 is 1.5 - 3.0 ng/lane. You mention that you have used the ant...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"