The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityab119441 is immunoreactive with sera from HBV-infected individuals.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 49% PBS, 50% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Core and e antigen
Hepatitis B Virus core antigen
RelevanceHepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection.
The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.