Recombinant Hepatitis C Virus NS3 + NS4 (mutated T54 A) protein (ab123539)

Overview

  • Product nameRecombinant Hepatitis C Virus NS3 + NS4 (mutated T54 A) protein
  • Protein lengthProtein fragment

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionB0B3F9
    • Amino acids1 to 217
    • Modificationsmutated T54 A

Specifications

Our Abpromise guarantee covers the use of ab123539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity1 unit of protease hydrolyzes 1 picomole of Ac-Asp-Glu-Dap(QXL™520)-Glu- Glu-Abu-COO-Ala -Ser-Cys(5-FAMsp)-NH2 per minute at pH 7.5 at 25° C. ab123539 is in the active form and the preactivation by pep4A or pep4AK is not necessary.
  • Applications

    Functional Studies

  • FormLiquid
  • Additional notes


    ab123539 is derived from its wild type (NCBIAccession: CAB46913) with a substitution of Thr54 with Ala. The mutations, T54A, conferred low to moderate levels of resistance (<20-fold) to NS3 protease inhibitor SCH503034.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

References for Recombinant Hepatitis C Virus NS3 + NS4 (mutated T54 A) protein (ab123539)

ab123539 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"