Recombinant HIV1 gp41 protein (ab49068)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • Molecular weight32 kDa
    • Amino acids466 to 753
    • Additional sequence informationβ-galactosidase (114 kDa) fused at the N- terminus.

Specifications

Our Abpromise guarantee covers the use of ab49068 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityReacts strongly with human HIV positive serum.
  • Applications

    ELISA

    Western blot

  • Purity> 95 % by SDS-PAGE.

  • FormLiquid
  • Additional notesReacts strongly with human HIV positive serum.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 8M Urea, 20mM Tris HCl, 10mM Beta mercaptoethanol, pH 8

General Info

  • Alternative names
    • Env
    • Glycoprotein 41
    • gp41
    • Human Immunodeficiency Virus 1
    • TM
    • Transmembrane protein
    see all
  • Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.

References for Recombinant HIV1 gp41 protein (ab49068)

ab49068 has not yet been referenced specifically in any publications.

Product Wall

The recombinant HIV1 gp41 protein is from a.a 466 to a.a 753 of the HIV-1 env region and is 32 kDa.


The only fusion is β-galactosidase (114 kDa) fused at the N- terminus.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"