Recombinant HIV1 + HIV2 envelope antigen protein (ab48966)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli

Specifications

Our Abpromise guarantee covers the use of ab48966 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Detects all HIV1,2 infected individuals responding to HIV1,2 envelope proteins.
  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Detects all HIV1,2 infected individuals responding to HIV1,2 envelope proteins.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA

General Info

  • Alternative names
    • Envelope glycoprotein gp160
    • Glycoprotein 120
    • Glycoprotein 41
    • gp120
    • gp41
    see all
  • Relevance
    Inhibitors targeting HIV1 viral envelope proteins are used as antiretroviral drugs. The surface protein gp120 attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. The transmembrane protein gp41 acts as a class I viral fusion protein.

References

ab48966 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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