Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Amino acids
      1 to 101

Specifications

Our Abpromise guarantee covers the use of ab83353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    ab83353 reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum.
  • Applications

    Blocking

    Western blot

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Lyophilised
  • Additional notes
    ab83353 reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C.

    Preservative: None
    Constituents: 0.1% Glycerol

  • Reconstitution
    The protein should be reconstituted in apirogenic sterile water or PBS buffer. The reconstituted solution has to be used immediately.

General Info

  • Alternative names
    • p14
    • Protein Tat
    • Transactivating regulatory protein
  • Relevance
    HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
  • Cellular localization
    Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.

References

This product has been referenced in:
  • Qu J  et al. The Tat protein of human immunodeficiency virus-1 enhances hepatitis C virus replication through interferon gamma-inducible protein-10. BMC Immunol 13:15 (2012). Read more (PubMed: 22471703) »

See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab83353.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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