The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% Purified via His tag. ab116442 was purified by Ni2+-NTA agarose
Additional notesab116442 was alkylated, digested with trypsin and the mass of the resultant peptides determined by MADLI-TOF/TOF. The peptides obtained gave 67% sequence coverage of 14-3-3 eta.
Theoretical pI: 5.3
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein 1
Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein eta polypeptide
Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, eta isoform
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
Tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide
FunctionAdapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Tissue specificityExpressed mainly in the brain and present in other tissues albeit at lower levels.
Sequence similaritiesBelongs to the 14-3-3 family.