The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
5 HT 2B
5 HT 2B receptor
5 hydroxytryptamine (serotonin) receptor 2B
5 hydroxytryptamine (serotonin) receptor 2B G protein coupled
5 hydroxytryptamine 2B receptor
5 hydroxytryptamine receptor 2B
5-hydroxytryptamine receptor 2B
SEROTONIN 5HT2B RECEPTOR
Serotonin receptor 2B
Stomach fundus serotonin receptor
FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
Tissue specificityExpressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.