Recombinant Human 5HT2C Receptor protein (ab114363)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MVNLRNAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPD GV
    • Molecular weight
      31 kDa including tags
    • Amino acids
      1 to 52

Associated products

Specifications

Our Abpromise guarantee covers the use of ab114363 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 5 Hydroxytryptamine 2C receptor
    • 5-HT-1C
    • 5-ht-1c receptor
    • 5-HT-2C
    • 5-HT1C
    • 5-HT2C
    • 5-HTR2C
    • 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
    • 5-hydroxytryptamine receptor 1C
    • 5-hydroxytryptamine receptor 2C
    • 5HT1C
    • 5HT2C
    • 5HT2C_HUMAN
    • 5HTR2C
    • 5Hydroxytryptamine 2C receptor
    • Htr1c
    • HTR2C
    • serotonin 1c receptor
    • serotonin 2c receptor
    • Serotonin 5-HT-2C receptor
    • Serotonin receptor 2C
    see all
  • Function
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Domain
    The PDZ domain-binding motif is involved in the interaction with MPDZ.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE showing ab114363 at approximately 31.35kDa stained with Coomassie Blue.

References

ab114363 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for contacting us.


The QC method for ab114363 and ab132415 is CBR staining. When testing the lab loaded 5uL for quantification.


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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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