Recombinant Human 5HT4 Receptor protein (ab158717)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQL RKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLD VLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPT FISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA FYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHR MRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTT INGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
    • Amino acids
      1 to 388
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 5 HT 4
    • 5 HT4
    • 5 HT4R
    • 5 hydroxytryptamine (serotonin) receptor 4, G protein coupled
    • 5 hydroxytryptamine 4 receptor
    • 5 hydroxytryptamine receptor 4
    • 5 hydroxytryptamine serotonin receptor 4
    • 5 hydroxytryptamine4 receptor
    • 5-HT-4
    • 5-ht4
    • 5-HT4R
    • 5H4
    • 5HT 4
    • 5HT4
    • 5ht4 receptor
    • 5HT4R
    • Cardiac 5 HT4 receptor
    • HTR 4
    • HTR4
    • serotonin 4 receptor
    • Serotonin 5 HT4 receptor
    • serotonin 5-ht-4 receptor
    • serotonin 5-ht-4a
    • Serotonin receptor 4
    see all
  • Relevance
    The 5HT4 Receptor is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulates adenylate cyclase. 5HT4a receptors may play a role in opioid-induced respiratory depression.
  • Cellular localization
    Cell membrane; Multi-pass membrane protein. Endosome. Note: Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli.

Images

  • ab158717 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158717 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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