Overview

  • Product name
    Recombinant Human ABAT protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MENHHSPKGQRRFQRKGVIGAVFCRMSQSSPSRQGKEGCCREGTAYAKAY QFMASHLSLGKPVSTGSIPRFNKALFNKQAKCKPNHYSFIGLSMLSPENF SIGCKYSVWFSETKGF
    • Molecular weight
      39 kDa including tags

Specifications

Our Abpromise guarantee covers the use of ab152164 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

    SDS-PAGE

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • (S) 3 amino 2 methylpropionate transaminase
    • (S)-3-amino-2-methylpropionate transaminase
    • 4 aminobutyrate aminotransferase
    • 4 aminobutyrate aminotransferase, mitochondrial
    • 4-aminobutyrate aminotransferase
    • ABAT
    • FLJ17813
    • FLJ30272
    • GABA aminotransferase
    • GABA AT
    • GABA T
    • GABA transaminase
    • GABA transferase
    • GABA-AT
    • GABA-T
    • GABAT
    • GABT_HUMAN
    • Gamma amino N butyrate transaminase
    • Gamma-amino-N-butyrate transaminase
    • hCG1984265
    • L AIBAT
    • L-AIBAT
    • LAIBAT
    • mitochondrial
    • NPD009
    see all
  • Function
    Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
  • Tissue specificity
    Liver > pancreas > brain > kidney > heart > placenta.
  • Involvement in disease
    Defects in ABAT are a cause of gamma-aminobutyrate transaminase deficiency (GABA-AT deficiency) [MIM:613163]. The phenotype of this deficiency includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.
  • Sequence similarities
    Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  • Cellular localization
    Mitochondrion matrix.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE analysis of ab152164 stained with Coomassie Blue.

References

ab152164 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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