The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 1.000 Eu/µg
>95% by SDS-PAGE . ab185403 is greater than 95% pure as determined by SEC-HPLC and reducing SDS-PAGE.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 3X PBS.
Please aliquot the reconstituted solution. After reconstitution aliquot and store at < -20 degrees, avoid freeze/thaw cycles.
ATP binding cassette protein
ATP binding cassette sub family B (MDR/TAP) member 5
ATP binding cassette sub family B member 5
ATP-binding cassette sub-family B member 5
P glycoprotein ABCB5
Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas.
Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Also expressed in several malignant tissues.