Overview

  • Product name
    Recombinant Human ABCB6 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      24 kDa
    • Amino acids
      598 to 818
    • Tags
      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names
    • ABC
    • ABC transporter umat
    • ABC14
    • Abcb6
    • ABCB6_HUMAN
    • ATP binding cassette sub family B member 6, mitochondrial precursor
    • ATP binding cassette, sub family B (MDR/TAP), member 6
    • ATP-binding cassette half-transporter
    • ATP-binding cassette sub-family B member 6
    • ATP-binding cassette sub-family B member 6, mitochondrial
    • DUH3
    • LAN
    • MCOPCB7
    • mitochondrial
    • Mitochondrial ABC transporter 3
    • Mt ABC transporter 3
    • Mt-ABC transporter 3
    • MTABC3
    • P glycoprotein related protein
    • P-glycoprotein-related protein
    • PRP
    • Ubiquitously expressed mammalian ABC half transporter
    • Ubiquitously-expressed mammalian ABC half transporter
    • UMAT
    see all
  • Function
    Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
  • Tissue specificity
    Widely expressed. Highest expression in heart and skeletal muscles.
  • Sequence similarities
    Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • Developmental stage
    Highly expressed in fetal liver.
  • Cellular localization
    Mitochondrion outer membrane.
  • Information by UniProt

References

ab127452 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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