For the best experience on the Abcam website please upgrade to a modern browser such as
Product name Recombinant Human ACOX1 protein
Protein length Full length protein Description
Source Wheat germ
Amino Acid Sequence
Sequence MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHED LNFLTRSQRYEVAVRKSAIMVKKMREFGIADPDEIMWFKNFVHRGRPEPL DLHLGMFLPTLLHQATAEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGL ETIATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCY GLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRE NMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIA IRYSAVRHQSEMKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKE TYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHG YSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCG MVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAK NLQKEVIHRKSKEVAWNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKA IQAVLRSLCLLYSLYGISQNAGDFLQGSIMTEPQITQVNQRVKELLTLIR SDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNKAEVHESY KHLKSLQSKL
Molecular weight 99 kDa including tags
Amino acids 1 to 660 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notes Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.3% Glutathione, 0.79% Tris HCl
Function Catalyzes the desaturation of very long chain acyl-CoAs to 2-trans-enoyl-CoAs.
Pathway Lipid metabolism; peroxisomal fatty acid beta-oxidation.
Involvement in disease Defects in ACOX1 are the cause of adrenoleukodystrophy pseudoneonatal (Pseudo-NALD) [MIM:264470]; also known as peroxisomal acyl-CoA oxidase deficiency. Pseudo-NALD is a peroxisomal single-enzyme disorder. Clinical features include mental retardation, leukodystrophy, seizures, mild hepatomegaly, hearing deficit. Pseudo-NALD is characterized by increased plasma levels of very-long chain fatty cids, due to decreased or absent peroxisome acyl-CoA oxidase activity. Peroxisomes are intact and functioning.
Sequence similarities Belongs to the acyl-CoA oxidase family.
Cellular localization Peroxisome.
Information by UniProt
Recombinant Human ACOX1 protein images
References for Recombinant Human ACOX1 protein (ab114556)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"