Overview

  • Product name
    Recombinant Human ACSS1 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      29 kDa
    • Amino acids
      368 to 629

Specifications

Our Abpromise guarantee covers the use of ab126001 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names
    • ACAS2L
    • AceCS2
    • AceCS2L
    • Acetate CoA ligase 2
    • Acetate--CoA ligase 2
    • Acetyl CoA synthetase 2
    • Acetyl Coenzyme A synthetase 2 (AMP forming) like
    • Acetyl coenzyme A synthetase 2 like, mitochondrial
    • Acetyl-CoA synthetase 2
    • Acetyl-coenzyme A synthetase 2-like, mitochondrial
    • ACS2L_HUMAN
    • Acss1
    • Acyl CoA synthetase short chain family member 1
    • Acyl-CoA synthetase short-chain family member 1
    • FLJ45659
    • KIAA1846
    • MGC33843
    see all
  • Function
    Important for maintaining normal body temperature during fasting and for energy homeostasis. Essential for energy expenditure under ketogenic conditions (By similarity). Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).
  • Sequence similarities
    Belongs to the ATP-dependent AMP-binding enzyme family.
  • Post-translational
    modifications
    Reversibly acetylated on Lys-642. The acetyl-CoA synthase activity is inhibited by acetylation and activated by deacetylation.
  • Cellular localization
    Mitochondrion matrix.
  • Information by UniProt

References

ab126001 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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