The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride
ReconstitutionReconstitute with water to desired concentration.
Acetate CoA ligase 2
Acetate--CoA ligase 2
Acetyl CoA synthetase 2
Acetyl Coenzyme A synthetase 2 (AMP forming) like
Acetyl coenzyme A synthetase 2 like, mitochondrial
Acetyl-CoA synthetase 2
Acetyl-coenzyme A synthetase 2-like, mitochondrial
Acyl CoA synthetase short chain family member 1
Acyl-CoA synthetase short-chain family member 1
FunctionImportant for maintaining normal body temperature during fasting and for energy homeostasis. Essential for energy expenditure under ketogenic conditions (By similarity). Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).
Sequence similaritiesBelongs to the ATP-dependent AMP-binding enzyme family.
Post-translational modificationsReversibly acetylated on Lys-642. The acetyl-CoA synthase activity is inhibited by acetylation and activated by deacetylation.