Recombinant Human Activin Receptor Type IIA protein (ab125548)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      47 kDa including tags
    • Amino acids
      161 to 513
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab125548 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    Assessed by densitometry.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.00
    Preservative: 1.02% Imidazole
    Constituents: 0.002% PMSF, 0.81% Sodium phosphate, 0.004% DTT, 25% Glycerol, 1.74% Sodium chloride

General Info

  • Alternative names
    • Activin A receptor type IIA
    • Activin receptor type 2A
    • Activin receptor type IIA
    • Activin receptor type-2A
    • ACTR 2
    • ACTR IIA
    • ACTR-IIA
    • ACTR2
    • ACTRII
    • ACTRIIA
    • Acvr 2
    • Acvr 2A
    • Acvr2
    • ACVR2A
    • AVR2A_HUMAN
    • OTTHUMP00000197918
    see all
  • Function
    On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
  • Sequence similarities
    Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 protein kinase domain.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab125548.

References

ab125548 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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