Recombinant Human ADAM23 protein (ab125993)

Overview

  • Product name
    Recombinant Human ADAM23 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      AQVLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEETGVSHSRKFSKC SILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECY GLCCKKCSLSNGAHCSDGPCCNNTSCLFQPRGYECRDAVNECDITEYCTG DSGQCPPNLHKQDGYACNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKF CYEKLNTEGTEKGNCGKDGDRWIQCSKHDVFCGFLLCTNLTRAPRIGQLQ GEIIPTSFYHQGRVIDCSGAHVVLDDDTDVG
    • Amino acids
      426 to 706
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab125993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 0.2% Guanidine HCl

  • Reconstitution
    Reconstitute with water to desired concentration.it is suggested to dissolve directly in 250ul DDW and the final concentration is 0.2ug/ul.

General Info

  • Alternative names
    • A disintegrin and metalloproteinase domain 23
    • ADAM metallopeptidase domain 23
    • Disintegrin and metalloproteinase domain containing protein 23
    • MDC 3
    • MDC3
    • Metalloproteinase like disintegrin like and cysteine rich protein 3
    see all
  • Relevance
    ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions.
  • Cellular localization
    Single pass type I membrane protein. 3 isoforms produced by alternative splicing, gamma isoform is secreted.

References

ab125993 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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