This product is an active protein and may elicit a biological response in vivo, handle with caution.
Adenylate cyclase inhibiting G alpha protein
Adrenergic beta 2 receptor surf
beta 2 adrenoceptor
Beta 2 adrenoreceptor
GTP binding regulatory protein Gi alpha 2 chain
Guanine nucleotide binding protein G protein alpha inhibiting activity polypeptide 2
ADBR2 is a member of the G protein-coupled receptor superfamily. It is activated by the catecholamine epinephrine and couples to the G protein Gs to mediate adenylate cyclase activation. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
The G protein family of signal transducers includes 5 heterotrimers, which are most clearly distinguished by their different alpha chains; they have virtually identical beta chains and similar gamma chains. G protein alpha inhibitor chain 2 is a subunit of the G(i) G protein, whose role is in inhibiting adenylate cyclase activity in response to bound GTP. The G proteins possess GTPase activity and are components of a complex membrane signaling system that includes membrane bound receptors. The system exists to modulate extracellular signals as they are transmitted into the cell.
ADBR2: Cell Membrane
References for Recombinant human ADBR2 + Gia2 fusion protein (ab90752)
has not yet been referenced specifically in any publications.
Publishing research using ab90752? Please let us know so that we can cite the reference in this datasheet.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Get resources and offers direct to your inboxSign up