Recombinant human ADBR2 + GsaS fusion protein (ab90338)

Overview

  • Product name
    Recombinant human ADBR2 + GsaS fusion protein
  • Protein length
    Full length protein
  • Description
    Recombinant human ADBR2 + GsαS fusion protein

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab90338 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Receptor expression level 5.8 - 9.5 pmol/mg.
  • Applications

    Functional Studies

  • Form
    Liquid
  • Additional notes
    Receptor expression level 5.8 - 9.5 pmol/mg.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Adenylate cyclase stimulating G alpha protein
    • ADRB 2
    • ADRB2
    • ADRB2R
    • ADRBR
    • Adrenergic beta 2 receptor surface
    • B2AR
    • BAR
    • Beta 2 adrenoceptor
    • Beta 2 adrenoreceptor
    • BETA2AR
    • Catecholamine receptor
    • GNAS
    • GNAS 2
    • GNAS complex locus
    • GNAS2
    • GSP
    • Guanine nucleotide binding protein G(s) subunit alpha isoforms short
    see all
  • Relevance
    ADBR2 is a member of the G protein-coupled receptor superfamily. It is activated by the catecholamine epinephrine and couples to the G protein Gs to mediate adenylate cyclase activation. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. G-protein Alpha S Short is the short splice variant of the alpha subunit of the heterotrimeric G protein Gs.
  • Cellular localization
    beta 2 Adrenergic Receptor: Cell membrane; Multi-pass membrane protein.

References

ab90338 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab90338.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up