The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Specific activity: > 6.0 units/ml. One unit will convert 2.0 µmoles of ADP to ATP + AMP per minute at pH 7.5 at 25C.
>95% by SDS-PAGE .
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50 Constituents: 0.32% Tris HCl, 10% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Adenylate kinase 1
Adenylate kinase isoenzyme 1
Adenylate kinase soluble
ATP AMP transphosphorylase
ATP-AMP transphosphorylase 1
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth.
Involvement in disease
Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency [MIM:612631].