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Adenylate cyclase stimulating G alpha
Adrenergic beta 2 receptor surface
Beta 2 adrenoceptor
Beta 2 adrenoreceptor
GNAS complex locus
Guanine nucleotide binding protein G(s) subunit alpha
RelevanceADBR2 is a member of the G protein-coupled receptor superfamily. It is activated by the catecholamine epinephrine and couples to the G protein Gs to mediate adenylate cyclase activation. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli.
Cellular localizationADBR2: Cell Membrane
References for Recombinant human ADRB2 + GsaL-Leu227 fusion protein (ab90834)
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