Recombinant human ADRB2 +GsaL protein (ab90788)

Overview

  • Product name
    Recombinant human ADRB2 +GsaL protein
  • Protein length
    Full length protein
  • Description
    Recombinant human ADRB2 +GsαL protein

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab90788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Activity: 11.5 - 12.5 pmol/mg
  • Applications

    Functional Studies

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Adenylate cyclase stimulating G alpha protein
    • ADRB2R
    • Adrenergic beta 2 receptor surface
    • B2AR
    • BAR
    • Beta 2 adrenoreceptor
    • BETA2AR
    • GNAS
    • GNAS1
    • Guanine nucleotide binding protein (G protein) alpha stimulating activity polypeptide 1
    see all
  • Relevance
    ADRB2 is a member of the G protein-coupled receptor superfamily. It is activated by the catecholamine epinephrine and couples to the G protein Gs to mediate adenylate cyclase activation. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. GsaL is the long splice variant of the alpha-subunit of the heterotrimeric G-protein Gs. Gs activates the effector adenylate cyclase. GsaL differs from the short splice variant by a 15 amino acid insert between the ras-like domain and the alpha-helical domain.
  • Cellular localization
    ADBR2: Cell membrane; Multi pass membrane protein. GsaL Peripheral membrane protein

References

ab90788 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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