Overview

  • Product nameRecombinant Human AGXT protein
  • Protein lengthProtein fragment

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP21549
    • SpeciesHuman
    • SequenceEAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDH FDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTEALRAALQHCPKKKL
    • Molecular weight37 kDa including tags
    • Amino acids293 to 392

Associated products

Specifications

Our Abpromise guarantee covers the use of ab117019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

General Info

  • Alternative names
    • AGT
    • AGT1
    • Agxt
    • AGXT1
    • Alanine glyoxylate aminotransferase
    • Alanine glyoxylate aminotransferase3
    • Alanine--glyoxylate aminotransferase
    • EC 2.6.1.44
    • EC 2.6.1.51
    • Hepatic peroxisomal alanine glyoxylate aminotransferase
    • Hepatic peroxisomal alanine:glyoxylate aminotransferase
    • L alanine glyoxylate aminotransferase 1
    • MS773
    • PH1
    • Serine pyruvate aminotransferase
    • Serine--pyruvate aminotransferase
    • Serine--pyruvate aminotransferase, mitochondrial
    • Serine:pyruvate aminotransferase
    • SPAT
    • SPT
    • SPYA_HUMAN
    • TLH6
    see all
  • Tissue specificityLiver.
  • Involvement in diseaseDefects in AGXT are the cause of hyperoxaluria primary type 1 (HP1) [MIM:259900]; also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
  • Sequence similaritiesBelongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  • Cellular localizationPeroxisome. Mitochondrion matrix. Except in some HP1 patients where AGT is found in the mitochondrial matrix.
  • Information by UniProt

Recombinant Human AGXT protein images

  • 12.5% SDS-PAGE showing ab117019 at approximately 36.63 kDa.
    Stained with Coomassie Blue.

References for Recombinant Human AGXT protein (ab117019)

ab117019 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"