Recombinant Human AKR1B10 protein (ab85415)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMATFVELSTK AKMPIVGLGT WKSPLGKVKE AVKVAIDAGY RHIDCAYVYQ NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL KLSYLDVYLI HWPQGFKSGD DLFPKDDKGN AIGGKATFLD AWEAMEELVD EGLVKALGVS NFSHFQIEKL LNKPGLKYKP VTNQVECHPY LTQEKLIQYC HSKGITVTAY SPLGSPDRPW AKPEDPSLLE DPKIKEIAAK HKKTAAQVLI RFHIQRNVIV IPKSVTPARI VENIQVFDFK LSDEEMATIL SFNRNWRACN VLQSSHLEDY PFDAEY

Specifications

Our Abpromise guarantee covers the use of ab85415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab85415 is purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • AK1BA_HUMAN
    • AKR1B10
    • AKR1B11
    • AKR1B12
    • Aldo keto reductase family 1 member B10
    • aldo keto reductase family 1 member B11
    • Aldo-keto reductase family 1 member B10
    • Aldo-keto reductase family 1 member B10 (aldose reductase)
    • Aldo-keto reductase family 1 member B11 (aldose reductase-like)
    • Aldose reductase like
    • aldose reductase like 1
    • aldose reductase like peptide
    • Aldose reductase related protein
    • Aldose reductase-like
    • Aldose reductase-related protein
    • ALDRLn
    • ARL 1
    • ARL-1
    • ARL1
    • ARL1 Human small intestine reductase
    • ARP
    • hARP
    • HIS
    • HSI
    • SI reductase
    • Small intestine reductase
    see all
  • FunctionActs as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
  • Tissue specificityFound in many tissues. Highly expressed in small intestine, colon and adrenal gland.
  • Sequence similaritiesBelongs to the aldo/keto reductase family.
  • Cellular localizationLysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
  • Information by UniProt

Recombinant Human AKR1B10 protein images

  • 15% SDS-PAGE showing ab85415 at approximately 36kDa (3µg).

References for Recombinant Human AKR1B10 protein (ab85415)

ab85415 has not yet been referenced specifically in any publications.

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