Recombinant Human AKR1C2 protein (ab114784)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHID SAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALE RSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEA MEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQR KLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKR TPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN RNVRYLTLDIFAGPPNYPFSDEY
    • Molecular weight
      62 kDa including tags
    • Amino acids
      1 to 323

Specifications

Our Abpromise guarantee covers the use of ab114784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 2-dihydrobenzene-1
    • 2-diol dehydrogenase
    • 3 alpha HSD3
    • 3 alpha hydroxysteroid dehydrogenase type III
    • 3-alpha-HSD3
    • AK1C2_HUMAN
    • AKR1C pseudo
    • AKR1C2
    • Aldo keto reductase family 1 member C2
    • Aldo-keto reductase family 1 member C2
    • BABP
    • Bile acid binding protein
    • Chlordecone reductase homolog
    • Chlordecone reductase homolog HAKRD
    • DD
    • DD-2
    • DD/BABP
    • DD2
    • DDH 2
    • DDH2
    • Dihydrodiol dehydrogenase 2
    • Dihydrodiol dehydrogenase/bile acid binding protein
    • Dihydrodiol dehydrogenase/bile acid-binding protein
    • FLJ53800
    • HAKRD
    • HBAB
    • MCDR 2
    • MCDR2
    • OTTHUMP00000044759
    • Pseudo chlordecone reductase
    • SRXY8
    • Trans 1 2 dihydrobenzene 1 2 diol dehydrogenase
    • Trans-1
    • Type II dihydrodiol dehydrogenase
    • Type III 3 alpha hydroxysteroid dehydrogenase
    • Type III 3-alpha-hydroxysteroid dehydrogenase
    see all
  • Function
    Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.
  • Sequence similarities
    Belongs to the aldo/keto reductase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • ab114784 on 12.5% SDS-PAGE Stained with Coomassie Blue.

References

ab114784 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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