Recombinant human ALDH3A1 protein (ab93463)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MSKISEAVKR ARAAFSSGRT RPLQFRIQQL EALQRLIQEQ EQELVGALAA DLHKNEWNAY YEEVVYVLEE IEYMIQKLPE WAADEPVEKT PQTQQDELYI HSEPLGVVLV IGTWNYPFNL TIQPMVGAIA AGNAVVLKPS ELSENMASLL ATIIPQYLDK DLYPVINGGV PETTELLKER FDHILYTGST GVGKIIMTAA AKHLTPVTLE LGGKSPCYVD KNCDLDVACR RIAWGKFMNS GQTCVAPDYI LCDPSIQNQI VEKLKKSLKE FYGEDAKKSR DYGRIISARH FQRVMGLIEG QKVAYGGTGD AATRYIAPTI LTDVDPQSPV MQEEIFGPVL PIVCVRSLEE AIQFINQREK PLALYMFSSN DKVIKKMIAE TSSGGVAAND VIVHITLHSL PFGGVGNSGM GSYHGKKSFE TFSHRRSCLV RPLMNDEGLK VRYPPSPAKM TQH

Specifications

Our Abpromise guarantee covers the use of ab93463 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific activity is >5 units/ml and was obtained by measuring the increase of NADP in absorbance at 340 nm resulting from the reduction of NAD. One unit will oxidize 1.0 umole of acetaldehyde to acetic acid per minute at pH 8.0 at 25C in the presence of beta-NAD, potassium and thiols.
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 95 % SDS-PAGE.
    ab93463 is purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Acetaldehyde dehydrogenase 3
    • AHD 4
    • AHD C
    • AHD4
    • AHDC
    • AL3A1_HUMAN
    • Aldehyde dehydrogenase
    • Aldehyde dehydrogenase 3
    • Aldehyde dehydrogenase 3 family member A1
    • Aldehyde dehydrogenase 3A1
    • Aldehyde dehydrogenase class 3
    • Aldehyde dehydrogenase dimeric NADP preferring
    • Aldehyde dehydrogenase family 3 member A1
    • Aldehyde dehydrogenase family 3 subfamily A1
    • Aldehyde dehydrogenase family 3, subfamily A, member 1
    • Aldehyde dehydrogenase isozyme 3
    • Aldehyde dehydrogenase type III
    • ALDH 3
    • ALDH 3A1
    • ALDH III
    • ALDH, stomach type
    • ALDH3
    • ALDH3 A1
    • ALDH3A 1
    • Aldh3a1
    • ALDHIII
    • dimeric NADP-preferring
    • MGC10406
    • Stomach aldehyde dehydrogenase
    • Tumor associated aldehyde dehydrogenase tumor ALDH
    see all
  • FunctionALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
  • Tissue specificityHigh levels in stomach, esophagus and lung; low level in the liver and kidney.
  • Sequence similaritiesBelongs to the aldehyde dehydrogenase family.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Recombinant human ALDH3A1 protein images

  • 15% SDS-PAGE analysis of ab93463 (3µg).

References for Recombinant human ALDH3A1 protein (ab93463)

ab93463 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your reply. The specific information activity for these products is as follows:


ab87415: Specific activity is > 0.14 units/ml

ab93463 and ab117154: Specific activity is > 0.5 units/ml

The protocol used...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"