Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.
Widely expressed, with highest expression in pancreas, ovary and spleen.
Belongs to the alkB family.
Cytoplasm. Nucleus. Midbody. Associates with the contractile ring and midbody.