Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionQ99217
    • SpeciesHuman
    • SequenceMGTWILFACLLGAAFAMPLPPHPGHPGYINFSYEVLTPLKWYQSIRPPYP SYGYEPMGGWLHHQIIPVLSQQHPPTHTLQPHHHIPVVPAQQPVIPQQPM MPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQPQPPVHPMQ PLPPQPPLPPMFPMQPLPPMLPDLTLEAWPSTDKTKREEVD
    • Molecular weight47 kDa including tags
    • Amino acids1 to 191

Specifications

Our Abpromise guarantee covers the use of ab114629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • AI1E
    • AIH1
    • ALGN
    • Amel
    • Amelogenesis imperfecta 1
    • Amelogenin
    • Amelogenin (amelogenesis imperfecta 1, X linked)
    • Amelogenin (X chromosome)
    • Amelogenin (X chromosome, amelogenesis imperfecta 1)
    • Amelogenin X isoform
    • Amelogenin, X linked
    • AMELX
    • AMELX_HUMAN
    • Amg
    • AMGL
    • AMGX
    • OTTHUMP00000022906
    • OTTHUMP00000022907
    • X isoform
    see all
  • FunctionPlays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
  • Involvement in diseaseDefects in AMELX are the cause of amelogenesis imperfecta hypoplastic type 1 (AIH1) [MIM:301200]. AIH1 is a X-linked defect of dental enamel formation. Teeth have only a thin layer of enamel with normal hardness. The thinness of the enamel makes the teeth appear small.
  • Sequence similaritiesBelongs to the amelogenin family.
  • Developmental stageTransiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt

Recombinant Human AMELX protein images

  • ab114629 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

References for Recombinant Human AMELX protein (ab114629)

ab114629 has not yet been referenced specifically in any publications.

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