Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      26 kDa
    • Amino acids
      207 to 440

Specifications

Our Abpromise guarantee covers the use of ab126005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names
    • AMH type II receptor
    • AMHR
    • AMHR2
    • AMHR2_HUMAN
    • Anti Mullerian hormone receptor, type II
    • Anti-Muellerian hormone type II receptor
    • Anti-Muellerian hormone type-2 receptor
    • MGC141312
    • MIS type II receptor
    • MISR2
    • MISRII
    • MRII
    • Muellerian hormone type 2 receptor
    • Muellerian hormone type II receptor
    • Muellerian inhibiting substance type II receptor
    • Mullerian hormone receptor type II
    • Mullerian inhibiting substance type II receptor
    see all
  • Function
    On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
  • Involvement in disease
    Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS2) [MIM:261550]. PMDS2 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
  • Sequence similarities
    Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 protein kinase domain.
  • Cellular localization
    Membrane.
  • Information by UniProt

References for Recombinant Human AMHR2 protein (ab126005)

ab126005 has not yet been referenced specifically in any publications.

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