Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ16671
    • SpeciesHuman
    • Molecular weight26 kDa
    • Amino acids207 to 440

Specifications

Our Abpromise guarantee covers the use of ab126005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • ReconstitutionReconstitute with water to desired concentration.

General Info

  • Alternative names
    • AMH type II receptor
    • AMHR
    • AMHR2
    • AMHR2_HUMAN
    • Anti Mullerian hormone receptor, type II
    • Anti-Muellerian hormone type II receptor
    • Anti-Muellerian hormone type-2 receptor
    • MGC141312
    • MIS type II receptor
    • MISR2
    • MISRII
    • MRII
    • Muellerian hormone type 2 receptor
    • Muellerian hormone type II receptor
    • Muellerian inhibiting substance type II receptor
    • Mullerian hormone receptor type II
    • Mullerian inhibiting substance type II receptor
    see all
  • FunctionOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
  • Involvement in diseaseDefects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS2) [MIM:261550]. PMDS2 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Information by UniProt

References for Recombinant Human AMHR2 protein (ab126005)

ab126005 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab126005.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"