Recombinant human ANGPTL3 protein (ab109135)

Overview

Description

  • NatureRecombinant
  • SourceHEK 293 cells
  • Amino Acid Sequence
    • AccessionQ9Y5C1
    • SpeciesHuman
    • Molecular weight60 kDa including tags
    • Amino acids1 to 460
    • TagsDDDDK tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab109135 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityActivates ERK phosphorylation in THP-1 cells.
  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level< 0.100 Eu/µg
  • Purity> 90 % SDS-PAGE.
    ab109135 is 0.2 µm filtered.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • ANG 5
    • ANG-5
    • ANG5
    • Angiopoietin 5
    • Angiopoietin like 3
    • Angiopoietin related protein 3
    • Angiopoietin-5
    • Angiopoietin-like protein 3
    • Angiopoietin-related protein 3
    • ANGL3_HUMAN
    • ANGPT5
    • ANGPTL3
    • ANL3
    • FHBL2
    • OTTHUMP00000010719
    • UNQ153/PRO179
    see all
  • Tissue specificityExpressed principally in liver. Weakly expressed in kidney.
  • Sequence similaritiesContains 1 fibrinogen C-terminal domain.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant human ANGPTL3 protein images

  • ERK phosphorylation induced by ab109135 in THP-1 cells.
    THP-1 monocyte cells were serum starved for 16 hr and then stimulated with ab109135 (500 ng/ml) for 1, 2 and 3 hrs, respectively. Antibodies against pERK1/2 and total ERK1/2 were used for immunoblotting.

References for Recombinant human ANGPTL3 protein (ab109135)

ab109135 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"