Recombinant human ANGPTL3 protein (ab109135)

Overview

Description

  • Nature
    Recombinant
  • Source
    HEK 293 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      60 kDa including tags
    • Amino acids
      1 to 460
    • Tags
      DDDDK tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab109135 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Activates ERK phosphorylation in THP-1 cells.
  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level
    < 0.100 Eu/µg
  • Purity
    > 90 % SDS-PAGE.
    ab109135 is 0.2 µm filtered.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • ANG 5
    • ANG-5
    • ANG5
    • Angiopoietin 5
    • Angiopoietin like 3
    • Angiopoietin related protein 3
    • Angiopoietin-5
    • Angiopoietin-like protein 3
    • Angiopoietin-related protein 3
    • ANGL3_HUMAN
    • ANGPT5
    • ANGPTL3
    • ANL3
    • FHBL2
    • OTTHUMP00000010719
    • UNQ153/PRO179
    see all
  • Tissue specificity
    Expressed principally in liver. Weakly expressed in kidney.
  • Sequence similarities
    Contains 1 fibrinogen C-terminal domain.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • ERK phosphorylation induced by ab109135 in THP-1 cells.
    THP-1 monocyte cells were serum starved for 16 hr and then stimulated with ab109135 (500 ng/ml) for 1, 2 and 3 hrs, respectively. Antibodies against pERK1/2 and total ERK1/2 were used for immunoblotting.

References

ab109135 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab109135.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up