Recombinant Human APLP2 protein (ab114600)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEP QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQI TNVMEANQRVSIDNWCRRDKKQCKSRFVTPFKCLVPPTPLPTNDVDVYFE TSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQT LIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAAL QSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQV MTHLHVIEERRNQTLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASI SETPVDVRVSSEESEEIPPFHPFHPFPALPENEGSGVGEQDGGLIGAEEK VINSKNKVDENMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLS SSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERH LNKMQNHGYENPTYKYLEQMQI
    • Molecular weight
      83 kDa including tags
    • Amino acids
      1 to 522

Specifications

Our Abpromise guarantee covers the use of ab114600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • amyloid beta (A4) precursor like protein 2
    • Amyloid like protein 2
    • Amyloid precursor protein homolog HSD 2
    • amyloid precursor protein homolog HSD2
    • Amyloid protein homolog
    • Amyloid-like protein 2
    • APLP-2
    • Aplp2
    • APLP2_HUMAN
    • APPH
    • APPL2
    • CDEBP
    • CDEI box binding protein
    • CDEI box-binding protein
    see all
  • Function
    May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
  • Tissue specificity
    Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
  • Sequence similarities
    Belongs to the APP family.
    Contains 1 BPTI/Kunitz inhibitor domain.
  • Post-translational
    modifications
    The BPTI/Kunitz inhibitor domain is O-glycosylated.
  • Cellular localization
    Cell membrane. Nucleus.
  • Information by UniProt

Images

  • ab114600 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References

ab114600 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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