Recombinant Human Apolipoprotein B (ab80037)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Amino acids
      1406 to 1606
    • Additional sequence information
      E. coli derived ApoB100 fusion protein with His tag

Specifications

Our Abpromise guarantee covers the use of ab80037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

  • Reconstitution
    Redissolve the powder with 1ml sterile water will restore to the original concentration 1mg/ml.

General Info

  • Alternative names
    • Apo B-100
    • Apo B-48
    • APOB
    • ApoB 100
    • ApoB 48
    • APOB_HUMAN
    • Apolipoprotein B
    • Apolipoprotein B (including Ag(x) antigen)
    • Apolipoprotein B 100
    • Apolipoprotein B-48
    • Apolipoprotein B48
    • FLDB
    • LDLCQ4
    see all
  • Function
    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • Involvement in disease
    Hypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • Sequence similarities
    Contains 1 vitellogenin domain.
  • Post-translational
    modifications
    Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • Cellular localization
    Cytoplasm. Secreted.
  • Information by UniProt

Recombinant Human Apolipoprotein B images

  • 20% SDS-PAGE gel analysis showing ab80037 at approximately 31 kDa. Commassie blue staining.

References for Recombinant Human Apolipoprotein B (ab80037)

ab80037 has not yet been referenced specifically in any publications.

Product Wall

The protein was lyophilized from 1x PBS and there is no BSA or other protein in the buffer. If the solution is cloudy we don't expect there to be an issue with the quality, however if there is precipitate we suggest adding more water and agitating the ...

Read More

We have heard back from the lab regarding your inquiry about an ApoB antibody specific to the region from which the peptide ab80037 has been created. Unfortunately, the lab has not produced an antibody agaist this antigen. In review of our catalog, whi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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