Recombinant human Apolipoprotein H (ab73695)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman
    • Molecular weight38 kDa
    • Additional sequence informationApolipoprotein-H Human Recombinant produced in SF9 is a glycosylated, polypeptide chain containing 326 amino acids and having a molecular mass of 38,200 Dalton (excluding glycosylation).

Specifications

Our Abpromise guarantee covers the use of ab73695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityab73695 is reactive with Goodpasture patient sera.
  • Applications

    Western blot

    ELISA

  • Purity> 90 % SDS-PAGE.
    ab73695 purified by proprietary chromatographic techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 200mM Sodium chloride, 16mM HEPES, pH 7.2

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Activated protein C binding protein
    • Activated protein C-binding protein
    • Anticardiolipin cofactor
    • APC inhibitor
    • Apo-H
    • APOH
    • APOH_HUMAN
    • Apolipoprotein H
    • apolipoprotein H (beta-2-glycoprotein I)
    • B2G1
    • B2GP1
    • B2GPI
    • Beta 2 glycoprotein I
    • Beta 2 glycoprotein I precursor
    • Beta(2)GPI
    • Beta-2-glycoprotein 1
    • Beta-2-glycoprotein I
    • BG
    • Glycoprotein 1, beta-2
    • Glycoprotein I, beta-2
    • OTTMUSP00000003033
    see all
  • FunctionBinds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
  • Tissue specificityExpressed by the liver and secreted in plasma.
  • Sequence similaritiesContains 4 Sushi (CCP/SCR) domains.
  • Post-translational
    modifications
    N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant human Apolipoprotein H (ab73695)

ab73695 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"