ARD1 homolog A N acetyltransferase (S. cerevisiae)
N acetyltransferase ARD1, human homolog of
N alpha acetyltransferase 10 NatA catalytic subunit
N terminal acetyltransferase complex ARD1 subunit homolog A
N(alpha) acetyltransferase 10 NatA catalytic subunit
N-terminal acetyltransferase complex ARD1 subunit homolog A
NatA catalytic subunit
FunctionIn complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation.
Sequence similaritiesBelongs to the acetyltransferase family. ARD1 subfamily. Contains 1 N-acetyltransferase domain.
Post-translational modificationsCleaved by caspases during apoptosis.
Cellular localizationCytoplasm. Nucleus. According to PubMed:12464182 it is cytoplasmic. According to PubMed:15496142, it is nuclear and cytoplasmic. Also present in the free cytosolic and cytoskeleton-bound polysomes.