Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP78540
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MVHSVAVIGA PFSQGQKRKG VEHGPAAIRE AGLMKRLSSL GCHLKDFGDL SFTPVPKDDL YNNLIVNPRS VGLANQELAE VVSRAVSDGY SCVTLGGDHS LAIGTISGHA RHCPDLCVVW VDAHADINTP LTTSSGNLHG QPVSFLLREL QDKVPQLPGF SWIKPCISSA SIVYIGLRDV DPPEHFILKN YDIQYFSMRD IDRLGIQKVM ERTFDLLIGK RQRPIHLSFD IDAFDPTLAP ATFTPVVGGL TYREGMYIAE EIHNTGLLSA LDLVEVNPQL ATSEEEAKTT ANLAVDVIAS SFGQTREGGH IVYDQLPTPS SPDESENQAR VRI.
    • Molecular weight38 kDa including tags
    • Amino acids23 to 354
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab116403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab116403 was purified by proprietary chromatographic techniques and filter sterilized.
  • FormLiquid
  • Additional notesAlthough stable at 4°C for 1 week, ab116403 should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 10% Glycerol, 0.32% Tris HCl

General Info

  • Alternative names
    • ARG2
    • ARGI2_HUMAN
    • Arginase II mitochondrial
    • Arginase type II
    • Arginase-2
    • arginase-2, mitochondrial
    • Kidney arginase
    • Kidney type arginase
    • Kidney-type arginase
    • L arginine amidinohydrolase
    • L arginine ureahydrolase
    • mitochondrial
    • Non hepatic arginase
    • Non-hepatic arginase
    • Nonhepatic arginase
    • Type II arginase
    see all
  • FunctionMay play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
  • Tissue specificityExpressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
  • PathwayNitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
  • Sequence similaritiesBelongs to the arginase family.
  • Cellular localizationMitochondrion.
  • Information by UniProt

References for Recombinant Human Arg2 protein (ab116403)

ab116403 has not yet been referenced specifically in any publications.

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