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Full length protein
Amino Acid Sequence
MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQG ADAFDPEEYQFTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHW QVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKEN LLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPL LPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCN RCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKC NICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIV NQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNN LGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQL EAEIENLSWKVERADSYDRGDLENQMHIAEQRRRTLLKDFHDT
1 to 493
proprietary tag N-Terminus
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- all trans retinoic acid inducible RING finger
- Ari 2
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
Widely expressed with higher expression in granulocytes.
Protein modification; protein ubiquitination.
Belongs to the RBR family. Ariadne subfamily.
Contains 1 IBR-type zinc finger.
Contains 2 RING-type zinc fingers.
RING-type 1 and RING-type 2 are required for the inhibitory function in myelopoiesis.
Ubiquitinated. Ubiquitination promotes proteasomal degradation.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
has not yet been referenced specifically in any publications.
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