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Source Escherichia coli
Amino Acid Sequence
Sequence LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL
Molecular weight 18 kDa
Amino acids 25 to 182 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activity Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED 50 for this effect is 15-25 µg/ml.
Endotoxin level < 0.100 Eu/µg
Purity > 98
% SDS-PAGE. Purity is greater than 98% by SDS-PAGE gel and HPLC analyses.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Arginine rich mutated in early stage tumors
Arginine rich protein
Function Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Sequence similarities Belongs to the ARMET family.
Domain The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
Post-translational modifications May contain sialic acid residues.
Cellular localization Secreted.
Information by UniProt
References for Recombinant human ARMET protein (ab123227)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"