Overview

  • Product name
    Recombinant Human ASC-2 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      VGSHPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEP KEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPASASSSTKDITS AVQSKRRKSK
    • Amino acids
      1954 to 2063
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Activating signal cointegrator 2
    • AIB3
    • Amplified in breast cancer 3 protein
    • Cancer amplified transcriptional coactivator ASC 2
    • NCOA6
    • Nuclear receptor coactivator 6
    • Nuclear receptor coactivator RAP250
    • PPAR interacting protein
    • Thyroid hormone receptor binding protein
    see all
  • Relevance
    The protein encoded by this gene is a nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone dependent fashion. It is involved in the coactivation of different nuclear receptors, such as steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). It probably functions as a general coactivator, rather than just a nuclear receptor coactivator,and may also be involved in the coactivation of the NFkB pathway (referenced from swissprot).
  • Cellular localization
    Nuclear

Images

  • ab161520 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161520 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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