Recombinant Human ATF3 protein (denatured) (ab109950)

Overview

  • Product name
    Recombinant Human ATF3 protein (denatured)
  • Protein length
    Full length protein
  • Description
    Recombinant Human ATF3 protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
    • Molecular weight
      21 kDa
    • Amino acids
      1 to 181

Specifications

Our Abpromise guarantee covers the use of ab109950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 20% Glycerol, 0.32% Tris HCl, 12% Urea

General Info

  • Alternative names
    • Activating transcription factor 3
    • ATF3
    • ATF3_HUMAN
    • ATF3deltaZip2
    • ATF3deltaZip2c
    • ATF3deltaZip3
    • cAMP dependent transcription factor ATF3
    • cAMP-dependent transcription factor ATF-3
    • Cyclic AMP dependent transcription factor ATF3
    • Cyclic AMP-dependent transcription factor ATF-3
    see all
  • Function
    This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
  • Sequence similarities
    Belongs to the bZIP family. ATF subfamily.
    Contains 1 bZIP domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • ab109950 at 3 ug on an SDS-PAGE gel (15%)

References

ab109950 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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