The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 1.000 Eu/µg
>95% by SDS-PAGE . Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Supplied as a 0.2 µM filtered solution.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40 Constituent: 100% PBS
APG4 autophagy 4 homolog A
ATG4 autophagy related 4 homolog A
ATG4 autophagy related 4 homolog A (S. cerevisiae)
AUT like 2 cysteine endopeptidase
AUT-like 2 cysteine endopeptidase
Autophagy related 4A cysteine peptidase
Autophagy related cysteine endopeptidase 2
Autophagy related protein 4 homolog A
Autophagy-related cysteine endopeptidase 2
Autophagy-related protein 4 homolog A
Cysteine protease ATG4A
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.