ATG4 autophagy related 4 homolog C (S. cerevisiae)
AUT (S. cerevisiae) like 1, cysteine endopeptidase
AUT like 1, cysteine endopeptidase
AUT like 1, cysteine endopeptidase (S. cerevisiae)
AUT like 3 cysteine endopeptidase
AUT-like 3 cysteine endopeptidase
Autophagy related 4C cysteine peptidase
Autophagy related cysteine endopeptidase 3
Autophagy related protein 4 homolog C
Autophagy-related cysteine endopeptidase 3
Autophagy-related protein 4 homolog C
Cysteine protease ATG4C
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Highly expressed in skeletal muscle, heart, liver and testis.